Brain and central nervous system cancer: clinical quality performance indicators - engagement document

Endnotes

1. Please note that surgical procedures include diagnostic biopsies.

2. WHO Classification of CNS tumours (2021) uses molecular parameters in addition to histology to define tumour entities.

3. Malignant gliomas include:

• Glioblastoma multiforme- GBM and its variants e.g. gliosarcoma
• Anaplastic Astrocytoma- AA
• Anaplastic pleomorphic xanthoastrocytoma
• Aanaplastic oligodendrogliomas
• Anaplastic (High-grade) ependymoma

4. Surgical techniques to aid the extent of resection include: 5ALA, Ultrasound, Intraoperative MRI, Intraoperative monitoring and awake craniotomy.

5. Percentage tumour reduction should be assessed by comparing pre-surgical imaging to post-surgical 72hr Magnetic Resonance Imaging (MRI).

6. Where it is not possible to image with MRI an attempt should be made to image with computerised tomography (CT).