Moorland grouse - Flubendazole use for parasitic worm control: preliminary environmental assessment

A report assessing the potential impact on the wider environment of the use of flubendazole in medicated grit.


Appendix A – Summary of flubendazole effects data

Duration Endpoint Effect Species scientific name Species common name Effect concentration (mg/l) Details Comment Reference
Acute data
Bacteria
30 min EC50 Luminescence inhibition V.fischeri Marine bacteria >0.3 Measured concentrations Study conducted to generally accepted procedures Wagil et al (2015)
Primary producers
48 h EC50 Growth rate L.minor Duckweed >1 Literature method. endpoint based on frond area. Measured concentrations Study conducted to generally accepted procedures Wagil et al (2015)
24 h EC50 Growth S.vacuolatus Green algae >1 Literature method Measured concentrations follows principles of OECD 201 (comparable sensitivity to 72 h test). Wagil et al (2015)
Invertebrates
48 h EC50 Immobility Daphnia magna Water flea 0.0665 Study details not retrieved Oh et al (2006)
48 h EC50 Mortality Daphnia magna Water flea 0.0701 OECD 202. Measured concentrations Study conducted to accepted method Bundschuh et al (2016)
48 h NOEC Mortality Daphnia magna Water flea 0.0074 OECD 202, measured concentrations Study conducted to accepted method Bundschuh et al (2016)
48 h EC50 Immobility Daphnia magna Water flea 0.045 OECD 202. Measured concentrations Study conducted to accepted method Wagil et al (2015)
48 h EC50 Immobility Daphnia magna Water flea 0.0448 OECD 202. Measured concentrations Study conducted to accepted method Puckowski et al (2017)
96 h EC50 Mortality Asellus aquaticus Aquatic sowbug >1 Measured concentrations Study conducted to generally accepted procedures Bundschuh et al (2016)
96 h EC50 Mortality Amphinemura sulcicollis Stone fly >1 Sediment free study (gauze mesh included). Study conducted to generally accepted procedures Bundschuh et al (2016)
24 h EC50 Mortality Caenorhabditis elegans Nemotode >1 Measured concentrations Study conducted to generally accepted procedures Bundschuh et al (2016)
24 h EC50 Mortality Brachionus calyciflorus Rotifer >8 Measured concentrations Study conducted to generally accepted procedures Bundschuh et al (2016)
96 h EC50 Mortality Dugesia gonocephala Flatworm 0.0219 Measured concentrations Study conducted to generally accepted procedures Bundschuh et al (2016)
96 h EC50 Mortality Tubifex tubifex Tubicified worm 0.0221 Sediment free test (quartz sand only). Measured concentrations Study conducted to generally accepted procedures Bundschuh et al (2016)
Chronic data
Invertebrates
21 days NOEC Growth Daphnia magna Water flea 0.0025 Study details not retrieved Oh et al (2006)
25 days NOEC Growth Daphnia magna Water flea 0.00625 Study details not retrieved Oh et al (2006)
21 days NOEC Reproduction Daphnia magna Water flea 0.01 Study details not retrieved Oh et al (2006)
25 days NOEC Reproduction Daphnia magna Water flea 0.025 Study details not retrieved Oh et al (2006)

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